CKD

Aetiology

  • Pre-renal
  • Renal
  • Post-Renal

Complications

Management

  • Treating aetiology if possible
  • Slowing down progression
  • Renal replacement Therapy
  • Complications (Ca, K)

Stages

1 to 5 based on eGFR

 

From Kumar and Clarke’s

Hypertension can be the cause or the result of renal disease.
It is often difficult to differentiate between the two on clinical
grounds.

Cross-transplantation experiments suggest that hypertension
travels with the kidney, in that hypertension will develop
in a normotensive recipient of a kidney genetically programmed
for hypertension. Similarly, patients with ESKD due
to hypertension become normotensive after receiving a renal
allograft from normotensive donors.

Patients with hypertension and normal renal function have a
significantly reduced number of nephrons in each kidney
alongside enlargement of the remaining glomeruli due to
glomerular hyperfiltration.